Wrote Letter L-080 of 1679-04-25 to Nehemiah Grew about living little animals in fish, hare, and dogs and his calculation that more than ten times as many living animals come from the milt of a cod as there are people living on the Earth

April 25, 1679
Standard reference information
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Text of the letter in the original Dutch and in English translation from Alle de Brieven / The Collected Letters at the DBNL - De Digitale Bibliotheek voor de Nederlandse Letteren.

The original manuscript on four folio pages, written and signed by Leeuwenhoek, is preserved at the Royal Society (MS. 1868. L1.40). Along with it is one page of calculations, explained, and an attached red-chalk drawing of the testicle of a dog.